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Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide.

An Ala-to-Thr substitution at position 59 activates the transforming properties of the p21ras protein without impairment of GTPase activity, a biochemical alteration associated with other activating mutations. To investigate the basis for the transforming properties of the Thr-59 mutant, we characte...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Lacal, J C, Aaronson, S A
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1986
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367201/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3540608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.12.4214
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