Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide.
An Ala-to-Thr substitution at position 59 activates the transforming properties of the p21ras protein without impairment of GTPase activity, a biochemical alteration associated with other activating mutations. To investigate the basis for the transforming properties of the Thr-59 mutant, we characte...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3540608/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.12.4214-4220.1986 |
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