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Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide.

An Ala-to-Thr substitution at position 59 activates the transforming properties of the p21ras protein without impairment of GTPase activity, a biochemical alteration associated with other activating mutations. To investigate the basis for the transforming properties of the Thr-59 mutant, we characte...

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Bibliografski detalji
Glavni autori: Lacal, J C, Aaronson, S A
Format: Artigo
Jezik:Inglês
Izdano: 1986
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC367201/
https://ncbi.nlm.nih.gov/pubmed/3540608
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