Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras.

A number of growth factors, including insulin and epidermal growth factor (EGF), induce accumulation of the GTP-bound form of p21ras. This accumulation could be caused either by an increase in guanine nucleotide exchange on p21ras or by a decrease in the GTPase activity of p21ras. To investigate whe...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Medema, R H, de Vries-Smits, A M, van der Zon, G C, Maassen, J A, Bos, J L
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358895/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8417322/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.155
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