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Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide.

An Ala-to-Thr substitution at position 59 activates the transforming properties of the p21ras protein without impairment of GTPase activity, a biochemical alteration associated with other activating mutations. To investigate the basis for the transforming properties of the Thr-59 mutant, we characte...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Lacal, J C, Aaronson, S A
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367201/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3540608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.12.4214-4220.1986
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