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Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange.

The neutralizing monoclonal antibody Y13-259 severely hampers the nucleotide exchange reaction between p21-bound and exogenous guanine nucleotides but does not interfere with the association of GDP to p21. These results suggest that the nucleotide exchange reaction is critical for p21 function. Inte...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Hattori, S, Clanton, D J, Satoh, T, Nakamura, S, Kaziro, Y, Kawakita, M, Shih, T Y
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 1987
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2439901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.5.1999-2002.1987
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