Neutralizing monoclonal antibody against ras oncogene product p21 which impairs guanine nucleotide exchange.

The neutralizing monoclonal antibody Y13-259 severely hampers the nucleotide exchange reaction between p21-bound and exogenous guanine nucleotides but does not interfere with the association of GDP to p21. These results suggest that the nucleotide exchange reaction is critical for p21 function. Inte...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Hattori, S, Clanton, D J, Satoh, T, Nakamura, S, Kaziro, Y, Kawakita, M, Shih, T Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365309/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2439901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.5.1999-2002.1987
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