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Identification of novel positive allosteric modulators and null modulators at the GABA(A) receptor α+β− interface

BACKGROUND AND PURPOSE: GABA(A) receptors are the major inhibitory neurotransmitter receptors in the mammalian brain and the target of many clinically important drugs interacting with different binding sites. Recently, we demonstrated that CGS 9895 (2-(4-methoxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5...

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Main Authors:	Varagic, Zdravko, Wimmer, Laurin, Schnürch, Michael, Mihovilovic, Marko D, Huang, Shengming, Rallapalli, Sundari, Cook, James M, Mirheydari, Pantea, Ecker, Gerhard F, Sieghart, Werner, Ernst, Margot
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Blackwell Publishing Ltd 2013
נושאים:	Research Papers
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3651663/ https://ncbi.nlm.nih.gov/pubmed/23472852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12151
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Identification of novel positive allosteric modulators and null modulators at the GABA(A) receptor α+β− interface

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