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Subtype selectivity of α+β− site ligands of GABA(A) receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors
BACKGROUND AND PURPOSE: GABA(A) receptors are the major inhibitory neurotransmitter receptors in the mammalian brain and the target of many clinically important drugs interacting with different binding sites. Recently, we demonstrated that CGS 9895 (2-(4-methoxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651664/ https://ncbi.nlm.nih.gov/pubmed/23472935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12153 |
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