Subtype selectivity of α+β− site ligands of GABA(A) receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors

BACKGROUND AND PURPOSE: GABA(A) receptors are the major inhibitory neurotransmitter receptors in the mammalian brain and the target of many clinically important drugs interacting with different binding sites. Recently, we demonstrated that CGS 9895 (2-(4-methoxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Varagic, Zdravko, Ramerstorfer, Joachim, Huang, Shengming, Rallapalli, Sundari, Sarto-Jackson, Isabella, Cook, James, Sieghart, Werner, Ernst, Margot
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651664/
https://ncbi.nlm.nih.gov/pubmed/23472935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12153
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados