Allosteric GABA(A) Receptor Modulators—A Review on the Most Recent Heterocyclic Chemotypes and Their Synthetic Accessibility †

GABA(A) receptor modulators are structurally almost as diverse as their target protein. A plethora of heterocyclic scaffolds has been described as modulating this extremely important receptor family. Some made it into clinical trials and, even on the market, some were dismissed. This review focuses...

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Veröffentlicht in:Molecules
Hauptverfasser: Vega Alanis, Blanca Angelica, Iorio, Maria Teresa, Silva, Luca L., Bampali, Konstantina, Ernst, Margot, Schnürch, Michael, Mihovilovic, Marko D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070463/
https://ncbi.nlm.nih.gov/pubmed/32102309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040999
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