Identification of novel positive allosteric modulators and null modulators at the GABA(A) receptor α+β− interface

BACKGROUND AND PURPOSE: GABA(A) receptors are the major inhibitory neurotransmitter receptors in the mammalian brain and the target of many clinically important drugs interacting with different binding sites. Recently, we demonstrated that CGS 9895 (2-(4-methoxyphenyl)-2H-pyrazolo[4,3-c]quinolin-3(5...

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Hlavní autoři: Varagic, Zdravko, Wimmer, Laurin, Schnürch, Michael, Mihovilovic, Marko D, Huang, Shengming, Rallapalli, Sundari, Cook, James M, Mirheydari, Pantea, Ecker, Gerhard F, Sieghart, Werner, Ernst, Margot
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
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Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651663/
https://ncbi.nlm.nih.gov/pubmed/23472852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12151
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