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Inhibition of Nonsense-Mediated RNA Decay Activates Autophagy
Nonsense-mediated RNA decay (NMD) is an mRNA surveillance mechanism which rapidly degrades select cytoplasmic mRNAs. We and others have shown that NMD is a dynamically regulated process inhibited by amino acid deprivation, hypoxia, and other cellular stresses commonly generated by the tumor microenv...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3648072/ https://ncbi.nlm.nih.gov/pubmed/23508110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00174-13 |
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