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Overexpression of the c-myc Oncogene Inhibits Nonsense-mediated RNA Decay in B Lymphocytes
The Myc transcription factor plays a vital role in both normal cellular physiology and in many human cancers. We have recently demonstrated that nonsense-mediated RNA decay (NMD), a mechanism that rapidly degrades select mRNAs, is inhibited by the stress-induced phosphorylation of translation initia...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220527/ https://ncbi.nlm.nih.gov/pubmed/21969377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266361 |
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