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Inhibition of Nonsense-Mediated RNA Decay by the Tumor Microenvironment Promotes Tumorigenesis

While nonsense-mediated RNA decay (NMD) is an established mechanism to rapidly degrade select transcripts, the physiological regulation and biological significance of NMD are not well characterized. We previously demonstrated that NMD is inhibited in hypoxic cells. Here we show that the phosphorylat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Ding, Zavadil, Jiri, Martin, Leenus, Parisi, Fabio, Friedman, Eugene, Levy, David, Harding, Heather, Ron, David, Gardner, Lawrence B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165546/
https://ncbi.nlm.nih.gov/pubmed/21730287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05704-11
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