Structural Basis for Molecular Recognition at Serotonin Receptors

Serotonin or 5-hydroxytryptamine (5-HT) regulates a wide spectrum of human physiology through the 5-HT receptor family. We report the crystal structures of the human 5-HT(1B) G protein-coupled receptor bound to the agonist anti-migraine medications ergotamine and dihydroergotamine. The structures re...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Chong, Jiang, Yi, Ma, Jinming, Wu, Huixian, Wacker, Daniel, Katritch, Vsevolod, Han, Gye Won, Liu, Wei, Huang, Xi-Ping, Vardy, Eyal, McCorvy, John D., Gao, Xiang, Zhou, Edward X., Melcher, Karsten, Zhang, Chenghai, Bai, Fang, Yang, Huaiyu, Yang, Linlin, Jiang, Hualiang, Roth, Bryan L., Cherezov, Vadim, Stevens, Raymond C., Xu, H. Eric
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644373/
https://ncbi.nlm.nih.gov/pubmed/23519210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1232807
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