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Human RECQ1 Interacts with Ku70/80 and Modulates DNA End-Joining of Double-Strand Breaks
Genomic instability is a known precursor to cancer and aging. The RecQ helicases are a highly conserved family of DNA-unwinding enzymes that play key roles in maintaining genome stability in all living organisms. Human RecQ homologs include RECQ1, BLM, WRN, RECQ4, and RECQ5β, three of which have bee...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641083/ https://ncbi.nlm.nih.gov/pubmed/23650516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062481 |
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