The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks

Replication requires homologous recombination (HR) to stabilize and restart terminally arrested forks. HR-mediated fork processing requires single stranded DNA (ssDNA) gaps and not necessarily double strand breaks. We used genetic and molecular assays to investigate fork-resection and restart at dys...

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Udgivet i:Nat Commun
Main Authors: Teixeira-Silva, Ana, Ait Saada, Anissia, Hardy, Julien, Iraqui, Ismail, Nocente, Marina Charlotte, Fréon, Karine, Lambert, Sarah A. E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719404/
https://ncbi.nlm.nih.gov/pubmed/29215009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02144-5
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