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Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape
DNA sequence is a major determinant of the binding specificity of transcription factors (TFs) for their genomic targets. However, eukaryotic cells often express, at the same time, TFs with highly similar DNA binding motifs but distinct in vivo targets. Currently, it is not well understood how TFs wi...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640701/ https://ncbi.nlm.nih.gov/pubmed/23562153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.03.014 |
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