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Using a structural and logics systems approach to infer bHLH–DNA binding specificity determinants

Numerous efforts are underway to determine gene regulatory networks that describe physical relationships between transcription factors (TFs) and their target DNA sequences. Members of paralogous TF families typically recognize similar DNA sequences. Knowledge of the molecular determinants of protein...

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Main Authors: De Masi, Federico, Grove, Christian A., Vedenko, Anastasia, Alibés, Andreu, Gisselbrecht, Stephen S., Serrano, Luis, Bulyk, Martha L., Walhout, Albertha J. M.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113581/
https://ncbi.nlm.nih.gov/pubmed/21335608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr070
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