PTPome profile of rheumatoid arthritis fibroblast-like synoviocytes: a novel role for SHP-2 as a modulator of invasion and survival

OBJECTIVE: The fibroblast-like synoviocytes (FLS) in the synovial intimal lining of the joint are key mediators of inflammation and joint destruction in rheumatoid arthritis (RA). In RA, these cells aggressively invade the extracellular matrix, producing cartilage-degrading proteases and inflammator...

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Bibliografische gegevens
Hoofdauteurs: Stanford, Stephanie M., Maestre, Michael F., Campbell, Amanda M., Bartok, Beatrix, Kiosses, William B., Boyle, David L., Arnett, Heather A., Mustelin, Tomas, Firestein, Gary S., Bottini, Nunzio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636201/
https://ncbi.nlm.nih.gov/pubmed/23335101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37872
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