Akt and mTORC1 Have Different Roles During Liver Tumorigenesis in Mice

BACKGROUND & AIMS: Phosphatidylinositide 3-kinase (PI3K) is deregulated in many human tumor types, including primary liver malignancies. The kinase Akt and mammalian target of rapamycin complex (mTORC1) are effectors of PI3K that promote cell growth and survival, but their individual roles in tu...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Kenerson, Heidi L., Yeh, Matthew M., Kazami, Machiko, Jiang, Xiuyun, Riehle, Kimberly J., McIntyre, Rebecca L., Park, James O., Kwon, Steve, Campbell, Jean S., Yeung, Raymond S.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633657/
https://ncbi.nlm.nih.gov/pubmed/23376645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.01.053
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items