Nalaganje...
mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice
Gastrointestinal cancers are frequently associated with chronic inflammation and excessive secretion of IL-6 family cytokines, which promote tumorigenesis through persistent activation of the GP130/JAK/STAT3 pathway. Although tumor progression can be prevented by genetic ablation of Stat3 in mice, t...
Shranjeno v:
| Main Authors: | , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2013
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561832/ https://ncbi.nlm.nih.gov/pubmed/23321674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65086 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|