Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis

The mechanistic target of rapamycin complex 2 (mTORC2) is a potentially novel and promising anticancer target due to its critical roles in proliferation, apoptosis, and metabolic reprogramming of cancer cells. However, the activity and function of mTORC2 in distinct cells within malignant tissue in...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Katholnig, Karl, Schütz, Birgit, Fritsch, Stephanie D., Schörghofer, David, Linke, Monika, Sukhbaatar, Nyamdelger, Matschinger, Julia M., Unterleuthner, Daniela, Hirtl, Martin, Lang, Michaela, Herac, Merima, Spittler, Andreas, Bergthaler, Andreas, Schabbauer, Gernot, Bergmann, Michael, Dolznig, Helmut, Hengstschläger, Markus, Magnuson, Mark A., Mikula, Mario, Weichhart, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824305/
https://ncbi.nlm.nih.gov/pubmed/31619583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124164
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge