Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis

The mechanistic target of rapamycin complex 2 (mTORC2) is a potentially novel and promising anticancer target due to its critical roles in proliferation, apoptosis, and metabolic reprogramming of cancer cells. However, the activity and function of mTORC2 in distinct cells within malignant tissue in...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:JCI Insight
Autores principales: Katholnig, Karl, Schütz, Birgit, Fritsch, Stephanie D., Schörghofer, David, Linke, Monika, Sukhbaatar, Nyamdelger, Matschinger, Julia M., Unterleuthner, Daniela, Hirtl, Martin, Lang, Michaela, Herac, Merima, Spittler, Andreas, Bergthaler, Andreas, Schabbauer, Gernot, Bergmann, Michael, Dolznig, Helmut, Hengstschläger, Markus, Magnuson, Mark A., Mikula, Mario, Weichhart, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824305/
https://ncbi.nlm.nih.gov/pubmed/31619583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124164
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares