mTORC1 Is Essential for Early Steps during Schwann Cell Differentiation of Amniotic Fluid Stem Cells and Regulates Lipogenic Gene Expression

Schwann cell development is hallmarked by the induction of a lipogenic profile. Here we used amniotic fluid stem (AFS) cells and focused on the mechanisms occurring during early steps of differentiation along the Schwann cell lineage. Therefore, we initiated Schwann cell differentiation in AFS cells...

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Detalhes bibliográficos
Main Authors: Preitschopf, Andrea, Li, Kongzhao, Schörghofer, David, Kinslechner, Katharina, Schütz, Birgit, Thi Thanh Pham, Ha, Rosner, Margit, Joo, Gabor Jozsef, Röhrl, Clemens, Weichhart, Thomas, Stangl, Herbert, Lubec, Gert, Hengstschläger, Markus, Mikula, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164523/
https://ncbi.nlm.nih.gov/pubmed/25221943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107004
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