Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis

Neural stem/progenitor cells (NSPCs) of the ventricular–subventricular zone (V-SVZ) are candidate cells of origin for many brain tumors. However, whether NSPCs in different locations within the V-SVZ differ in susceptibility to tumorigenic mutations is unknown. Here, single-cell measurements of sign...

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Enregistré dans:
Détails bibliographiques
Publié dans:Life Sci Alliance
Auteurs principaux: Rushing, Gabrielle V, Brockman, Asa A, Bollig, Madelyn K, Leelatian, Nalin, Mobley, Bret C, Irish, Jonathan M, Ess, Kevin C, Fu, Cary, Ihrie, Rebecca A
Format: Artigo
Langue:Inglês
Publié: Life Science Alliance LLC 2019
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435042/
https://ncbi.nlm.nih.gov/pubmed/30910807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800218
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