Fate-Mapping Evidence that Hepatic Stellate Cells are Epithelial Progenitors in Adult Mouse Livers

Liver injury activates quiescent (Q) hepatic stellate cells (HSC) to proliferative, myofibroblasts (MF). Accumulation of MF-HSC sometimes causes cirrhosis and liver failure. However, MF-HSC also promote liver regeneration by producing growth factors for oval cells, bipotent progenitors of hepatocyte...

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Detalhes bibliográficos
Main Authors: Yang, Liu, Jung, Youngmi, Omenetti, Alessia, Witek, Rafal P., Choi, Steve, Vandongen, Hendrika M, Huang, Jiawen, Alpini, Gianfranco D., Diehl, Anna Mae
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633413/
https://ncbi.nlm.nih.gov/pubmed/18511600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0115
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