Signals from Dying Hepatocytes Trigger Growth of Liver Progenitors

OBJECTIVE: The death rate of mature hepatocytes is chronically increased in various liver diseases, triggering responses that prevent liver atrophy, but often cause fibrosis. Mice with targeted disruption of Inhibitor kappa beta kinase (Ikk) in hepatocytes (HEP) provide a model to investigate this p...

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Huvudupphovsmän: Jung, Youngmi, Witek, Rafal P., Syn, Wing-Kin, Choi, Steve S., Omenetti, Alessia, Premont, Richard, Guy, Cynthia D., Diehl, Anna Mae
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632642/
https://ncbi.nlm.nih.gov/pubmed/20427400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2009.204354
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