Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

Myofibroblastic hepatic stellate cells (MF-HSC) are derived from quiescent hepatic stellate cells (Q-HSC). Q-HSC express certain epithelial cell markers and have been reported to form junctional complexes similar to epithelial cells. We have shown that Hedgehog (Hh) signaling plays a key role in HSC...

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Bibliografiske detaljer
Main Authors: Choi, Steve S., Omenetti, Alessia, Witek, Rafal P., Moylan, Cynthia A., Syn, Wing-Kin, Jung, Youngmi, Yang, Liu, Sudan, Debra L., Sicklick, Jason K., Michelotti, Gregory A., Rojkind, Marcos, Diehl, Anna Mae
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Liver and Biliary Tract
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850083/
https://ncbi.nlm.nih.gov/pubmed/19815628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00292.2009
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