Activation of Rac1 promotes Hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells

Hepatic accumulation of myofibroblastic hepatic stellate cells (MF-HSC) is pivotal in the pathogenesis of cirrhosis. Two events are necessary for MF-HSC to accumulate in damaged livers: transition of resident, quiescent HSC (Q-HSC) to MF-HSC, and expansion of MF-HSC numbers via increased proliferati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Choi, Steve S., Witek, Rafal P., Yang, Liu, Omenetti, Alessia, Syn, Wing-Kin, Moylan, Cynthia A., Jung, Youngmi, Karaca, Gamze F., Teaberry, Vanessa S., Pereira, Thiago A., Wang, Jiangbo, Ren, Xiu-Rong, Diehl, Anna Mae
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920128/
https://ncbi.nlm.nih.gov/pubmed/20578145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23649
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados