Sonic Hedgehog Is An Autocrine Viability Factor for Myofibroblastic Hepatic Stellate Cells

BACKGROUND/AIMS: Factors released during liver injury, such as platelet derived growth factor-BB (PDGF) promote accumulation of myofibroblastic hepatic stellate cells (MFB) that drive the pathogenesis of cirrhosis. The Hedgehog (Hh) pathway regulates remodeling of other injured tissues. This study e...

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Main Authors: Yang, Liu, Wang, Ying, Mao, Hua, Fleig, Susanne, Omenetti, Alessia, Brown, Kevin D., Sicklick, Jason K, Li, Yin-Xiong, Diehl, Anna Mae
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196213/
https://ncbi.nlm.nih.gov/pubmed/18022723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2007.07.032
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