Sonic Hedgehog Is An Autocrine Viability Factor for Myofibroblastic Hepatic Stellate Cells

BACKGROUND/AIMS: Factors released during liver injury, such as platelet derived growth factor-BB (PDGF) promote accumulation of myofibroblastic hepatic stellate cells (MFB) that drive the pathogenesis of cirrhosis. The Hedgehog (Hh) pathway regulates remodeling of other injured tissues. This study e...

Full description

Saved in:
Bibliographic Details
Main Authors: Yang, Liu, Wang, Ying, Mao, Hua, Fleig, Susanne, Omenetti, Alessia, Brown, Kevin D., Sicklick, Jason K, Li, Yin-Xiong, Diehl, Anna Mae
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196213/
https://ncbi.nlm.nih.gov/pubmed/18022723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2007.07.032
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items