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Sonic Hedgehog Is An Autocrine Viability Factor for Myofibroblastic Hepatic Stellate Cells
BACKGROUND/AIMS: Factors released during liver injury, such as platelet derived growth factor-BB (PDGF) promote accumulation of myofibroblastic hepatic stellate cells (MFB) that drive the pathogenesis of cirrhosis. The Hedgehog (Hh) pathway regulates remodeling of other injured tissues. This study e...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2196213/ https://ncbi.nlm.nih.gov/pubmed/18022723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2007.07.032 |
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