Viral Factors Induce Hedgehog Pathway Activation in Humans with Viral Hepatitis, Cirrhosis, and Hepatocellular Carcinoma

Hh pathway activation promotes many processes that occur during fibrogenic liver repair. Whether the Hh pathway modulates the outcomes of virally-mediated liver injury has never been examined. Gene-profiling studies of human hepatocellular carcinomas (HCC) demonstrate Hh pathway activation in HCCs r...

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Auteurs principaux: Pereira, Thiago de Almeida, Witek, Rafal P., Syn, Wing-Kin, Choi, Steve S., Bradrick, Shelton, Karaca, Gamze F, Agboola, Kolade M., Jung, Youngmi, Omenetti, Alessia, Moylan, Cynthia A., Yang, Liu, Fernandez-Zapico, Martin E., Jhaveri, Ravi, Shah, Vijay H., Pereira, Fausto E., Diehl, Anna Mae
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980808/
https://ncbi.nlm.nih.gov/pubmed/20697376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.147
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