Viral Factors Induce Hedgehog Pathway Activation in Humans with Viral Hepatitis, Cirrhosis, and Hepatocellular Carcinoma

Hh pathway activation promotes many processes that occur during fibrogenic liver repair. Whether the Hh pathway modulates the outcomes of virally-mediated liver injury has never been examined. Gene-profiling studies of human hepatocellular carcinomas (HCC) demonstrate Hh pathway activation in HCCs r...

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Hlavní autoři: Pereira, Thiago de Almeida, Witek, Rafal P., Syn, Wing-Kin, Choi, Steve S., Bradrick, Shelton, Karaca, Gamze F, Agboola, Kolade M., Jung, Youngmi, Omenetti, Alessia, Moylan, Cynthia A., Yang, Liu, Fernandez-Zapico, Martin E., Jhaveri, Ravi, Shah, Vijay H., Pereira, Fausto E., Diehl, Anna Mae
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980808/
https://ncbi.nlm.nih.gov/pubmed/20697376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.147
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