Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

Epithelial-mesenchymal transitions (EMTs) play an important role in tissue construction during embryogenesis, and evidence suggests that this process may also help to remodel some adult tissues after injury. Activation of the hedgehog (Hh) signaling pathway regulates EMT during development. This pat...

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Detalhes bibliográficos
Main Authors: Omenetti, Alessia, Porrello, Alessandro, Jung, Youngmi, Yang, Liu, Popov, Yury, Choi, Steve S., Witek, Rafal P., Alpini, Gianfranco, Venter, Juliet, Vandongen, Hendrika M., Syn, Wing-Kin, Baroni, Gianluca Svegliati, Benedetti, Antonio, Schuppan, Detlef, Diehl, Anna Mae
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542850/
https://ncbi.nlm.nih.gov/pubmed/18802480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35875
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