Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

Epithelial-mesenchymal transitions (EMTs) play an important role in tissue construction during embryogenesis, and evidence suggests that this process may also help to remodel some adult tissues after injury. Activation of the hedgehog (Hh) signaling pathway regulates EMT during development. This pat...

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Main Authors: Omenetti, Alessia, Porrello, Alessandro, Jung, Youngmi, Yang, Liu, Popov, Yury, Choi, Steve S., Witek, Rafal P., Alpini, Gianfranco, Venter, Juliet, Vandongen, Hendrika M., Syn, Wing-Kin, Baroni, Gianluca Svegliati, Benedetti, Antonio, Schuppan, Detlef, Diehl, Anna Mae
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542850/
https://ncbi.nlm.nih.gov/pubmed/18802480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35875
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