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‘Ryanopathy’: causes and manifestations of RyR2 dysfunction in heart failure
The cardiac ryanodine receptor (RyR2), a Ca(2+) release channel on the membrane of the sarcoplasmic reticulum (SR), plays a key role in determining the strength of the heartbeat by supplying Ca(2+) required for contractile activation. Abnormal RyR2 function is recognized as an important part of the...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633158/ https://ncbi.nlm.nih.gov/pubmed/23408344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt024 |
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