Persistence of Resistant Variants in Hepatitis C Virus-Infected Patients Treated with the NS5A Replication Complex Inhibitor Daclatasvir

Daclatasvir (DCV; BMS-790052) is a hepatitis C virus (HCV) NS5A replication complex inhibitor (RCI) with picomolar to low nanomolar potency and broad genotypic coverage in vitro. Viral RNA declines have been observed in the clinic for both alpha interferon-ribavirin (IFN-α–RBV) and IFN-RBV-free regi...

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Bibliografske podrobnosti
Main Authors: Wang, Chunfu, Sun, Jin-Hua, O'Boyle, Donald R., Nower, Peter, Valera, Lourdes, Roberts, Susan, Fridell, Robert A., Gao, Min
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632915/
https://ncbi.nlm.nih.gov/pubmed/23403428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02494-12
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