Persistence of Resistant Variants in Hepatitis C Virus-Infected Patients Treated with the NS5A Replication Complex Inhibitor Daclatasvir

Daclatasvir (DCV; BMS-790052) is a hepatitis C virus (HCV) NS5A replication complex inhibitor (RCI) with picomolar to low nanomolar potency and broad genotypic coverage in vitro. Viral RNA declines have been observed in the clinic for both alpha interferon-ribavirin (IFN-α–RBV) and IFN-RBV-free regi...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Wang, Chunfu, Sun, Jin-Hua, O'Boyle, Donald R., Nower, Peter, Valera, Lourdes, Roberts, Susan, Fridell, Robert A., Gao, Min
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632915/
https://ncbi.nlm.nih.gov/pubmed/23403428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02494-12
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk