Hepatitis C Virus RNA Elimination and Development of Resistance in Replicon Cells Treated with BMS-790052

BMS-790052, a first-in-class hepatitis C virus (HCV) replication complex inhibitor, targeting nonstructural protein 5A (NS5A), displays picomolar to nanomolar potency against genotypes 1 to 5. This exceptional potency translated into robust anti-HCV activity in clinical studies with HCV genotype 1-i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wang, Chunfu, Huang, Haichang, Valera, Lourdes, Sun, Jin-Hua, O'Boyle, Donald R., Nower, Peter T., Jia, Lingling, Qiu, Dike, Huang, Xin, Altaf, Aneela, Gao, Min, Fridell, Robert A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2012
विषय:
Antiviral Agents
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294925/
https://ncbi.nlm.nih.gov/pubmed/22214777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05977-11
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