In Vitro Activity of BMS-790052 on Hepatitis C Virus Genotype 4 NS5A

The antiviral profile of BMS-790052, a potent hepatitis C virus (HCV) replication complex inhibitor targeting nonstructural protein NS5A, is well characterized for HCV genotype-1. Here, we report that BMS-790052 inhibits hybrid replicons containing HCV genotype-4 NS5A genes with 50% effective concen...

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Autori principali: Wang, Chunfu, Jia, Lingling, Huang, Haichang, Qiu, Dike, Valera, Lourdes, Huang, Xin, Sun, Jin-Hua, Nower, Peter T., O'Boyle, Donald R., Gao, Min, Fridell, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294917/
https://ncbi.nlm.nih.gov/pubmed/22203595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06169-11
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