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In Vitro Activity of Daclatasvir on Hepatitis C Virus Genotype 3 NS5A
The NS5A replication complex inhibitor daclatasvir (DCV; BMS-790052) inhibits hybrid replicons containing hepatitis C virus (HCV) genotype 3a (HCV3a) NS5A genes with 50% effective concentrations (EC(50)s) ranging from 120 to 870 pM. Selection studies with a hybrid HCV3a replicon identified NS5A resi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535966/ https://ncbi.nlm.nih.gov/pubmed/23089758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01874-12 |
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