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Distinct Functions of NS5A in Hepatitis C Virus RNA Replication Uncovered by Studies with the NS5A Inhibitor BMS-790052

BMS-790052, targeting nonstructural protein 5A (NS5A), is the most potent hepatitis C virus (HCV) inhibitor described to date. It is highly effective against genotype 1 replicons and also displays robust genotype 1 anti-HCV activity in the clinic (M. Gao et al., Nature 465:96-100, 2010). BMS-790052...

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Detaylı Bibliyografya
Asıl Yazarlar: Fridell, Robert A., Qiu, Dike, Valera, Lourdes, Wang, Chunfu, Rose, Ronald E., Gao, Min
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126594/
https://ncbi.nlm.nih.gov/pubmed/21593143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00253-11
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