Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus

Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes global epidemics of a debilitating polyarthritis in humans. As there is a pressing need for the development of therapeutic agents, we screened 230 new mouse anti-CHIKV monoclonal antibodies (MAbs) for their ability to inhibit...

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Hoofdauteurs: Pal, Pankaj, Dowd, Kimberly A., Brien, James D., Edeling, Melissa A., Gorlatov, Sergey, Johnson, Syd, Lee, Iris, Akahata, Wataru, Nabel, Gary J., Richter, Mareike K. S., Smit, Jolanda M., Fremont, Daved H., Pierson, Theodore C., Heise, Mark T., Diamond, Michael S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630103/
https://ncbi.nlm.nih.gov/pubmed/23637602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003312
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