C1q Reduces the Stoichiometric Threshold for Antibody-Mediated Neutralization of West Nile Virus

Virus neutralization is governed by the number of antibodies that bind a virion during the cellular entry process. Cellular and serum factors that interact with antibodies have the potential to modulate neutralization potency. Although the addition of serum complement can increase the neutralizing a...

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Detalhes bibliográficos
Main Authors: Mehlhop, Erin, Nelson, Steevenson, Jost, Christiane A., Gorlatov, Sergey, Johnson, Syd, Fremont, Daved H., Diamond, Michael S., Pierson, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782387/
https://ncbi.nlm.nih.gov/pubmed/19837377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.09.003
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