Maturation of West Nile virus modulates sensitivity to antibody-mediated neutralization.

West Nile virions incorporate 180 envelope (E) proteins that orchestrate the process of virus entry and are the primary target of neutralizing antibodies. The E proteins of newly synthesized West Nile virus (WNV) are organized into trimeric spikes composed of pre-membrane (prM) and E protein heterod...

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Главные авторы: Steevenson Nelson, Christiane A Jost, Qinq Xu, Jessica Ess, Julie E Martin, Theodore Oliphant, Stephen S Whitehead, Anna P Durbin, Barney S Graham, Michael S Diamond, Theodore C Pierson
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2008-05-01
Серии:PLoS Pathogens
Online-ссылка:http://europepmc.org/articles/PMC2330159?pdf=render
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