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A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus

Neutralizing antibodies are a significant component of the host's protective response against flavivirus infection. Neutralization of flaviviruses occurs when individual virions are engaged by antibodies with a stoichiometry that exceeds a required threshold. From this “multiple-hit” perspectiv...

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Detalhes bibliográficos
Main Authors: Dowd, Kimberly A., Jost, Christiane A., Durbin, Anna P., Whitehead, Stephen S., Pierson, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128118/
https://ncbi.nlm.nih.gov/pubmed/21738473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002111
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