Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

HDAC inhibitors (HDACi) exert beneficial effects in mdx mice, by promoting endogenous regeneration; however, the cellular determinants of HDACi activity on dystrophic muscles have not been determined. We show that fibroadipogenic progenitors (FAP) influence the regeneration potential of satellite ce...

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Hauptverfasser: Mozzetta, Chiara, Consalvi, Silvia, Saccone, Valentina, Tierney, Matthew, Diamantini, Adamo, Mitchell, Kathryn J, Marazzi, Giovanna, Borsellino, Giovanna, Battistini, Luca, Sassoon, David, Sacco, Alessandra, Puri, Pier Lorenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: WILEY-VCH Verlag 2013
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628105/
https://ncbi.nlm.nih.gov/pubmed/23505062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202096
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