Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

HDAC inhibitors (HDACi) exert beneficial effects in mdx mice, by promoting endogenous regeneration; however, the cellular determinants of HDACi activity on dystrophic muscles have not been determined. We show that fibroadipogenic progenitors (FAP) influence the regeneration potential of satellite ce...

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Détails bibliographiques
Auteurs principaux: Mozzetta, Chiara, Consalvi, Silvia, Saccone, Valentina, Tierney, Matthew, Diamantini, Adamo, Mitchell, Kathryn J, Marazzi, Giovanna, Borsellino, Giovanna, Battistini, Luca, Sassoon, David, Sacco, Alessandra, Puri, Pier Lorenzo
Format: Artigo
Langue:Inglês
Publié: WILEY-VCH Verlag 2013
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628105/
https://ncbi.nlm.nih.gov/pubmed/23505062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202096
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