Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

HDAC inhibitors (HDACi) exert beneficial effects in mdx mice, by promoting endogenous regeneration; however, the cellular determinants of HDACi activity on dystrophic muscles have not been determined. We show that fibroadipogenic progenitors (FAP) influence the regeneration potential of satellite ce...

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Autori principali: Mozzetta, Chiara, Consalvi, Silvia, Saccone, Valentina, Tierney, Matthew, Diamantini, Adamo, Mitchell, Kathryn J, Marazzi, Giovanna, Borsellino, Giovanna, Battistini, Luca, Sassoon, David, Sacco, Alessandra, Puri, Pier Lorenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY-VCH Verlag 2013
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628105/
https://ncbi.nlm.nih.gov/pubmed/23505062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202096
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