HDAC inhibitors tune miRNAs in extracellular vesicles of dystrophic muscle‐resident mesenchymal cells

We show that extracellular vesicles (EVs) released by mesenchymal cells (i.e., fibro–adipogenic progenitors—FAPs) mediate microRNA (miR) transfer to muscle stem cells (MuSCs) and that exposure of dystrophic FAPs to HDAC inhibitors (HDACis) increases the intra‐EV levels of a subset of miRs, which coo...

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Detaylı Bibliyografya
Yayımlandı:EMBO Rep
Asıl Yazarlar: Sandonà, Martina, Consalvi, Silvia, Tucciarone, Luca, De Bardi, Marco, Scimeca, Manuel, Angelini, Daniela Francesca, Buffa, Valentina, D'Amico, Adele, Bertini, Enrico Silvio, Cazzaniga, Sara, Bettica, Paolo, Bouché, Marina, Bongiovanni, Antonella, Puri, Pier Lorenzo, Saccone, Valentina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507515/
https://ncbi.nlm.nih.gov/pubmed/32754983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050863
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