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Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket
Blockade of the angiotensin (ANG) II receptor type 1 (AT(1)R) with angiotensin receptor blockers (ARBs) is widely used in the treatment of hypertension. However, ARBs are variably effective in reducing blood pressure, likely due, in part, to polymorphisms in the ARB binding pocket of the AT(1)R. The...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Physiological Society
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625841/ https://ncbi.nlm.nih.gov/pubmed/23389452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00127.2012 |
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